Journal Club activity for Week 5
Week 5 (Presentation by all the 3 groups, due 3/7/14)
Journal club article : microtubule_migration.pdf
Web Link : http://www.nature.com/nrm/journal/v3/n12/full/nrm971.html
Present and discuss the experimental method, results and your own interpretation on Figures 1 and 2 (Group 1), Figures 3 and 4 (Group 2), Figures 5 and 6 (Group 3) and related movies from the above review article and the link.
Activities for Week 3 and Week 4 (Explain/Teach concepts to your peers)
Week 4 (Presentation by Group 1 due 2/21/14)
Group 1 - Kinesin walking models. Discuss in vitro experimental observations to support these models. http://www.stanford.edu/group/blocklab/kinesin/kinesin.html
Week 4 (Presentation by Group 2 and Group 3, due 2/21/14)
Group 2 - How motor proteins convert chemical energy to mechanical energy required for physical movement. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668149/
Group 3 - How can we study and perturb microtubule dynamics in vivo? Discuss an assay system to visualize microtubule plus end growth with fluorescent labeling using a particular model system. (Review your own literature)
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